PHENIBUT – What are the Benefits & Side Effects?

PHENIBUT:-What Are the Benefits & Side Effects of Phenibut?

Phenibut has a similar structure to gamma-aminobutyric acid (GABA), which is found in the brain. This supplement uses to treat various brain disorder such as anxiety, fear trouble sleeping, PTSD, depression, and alcoholism.

The IUPSC name or another name of phenibut is 4-Amino-3-Phenylbutyric Acid, Acide 4-Amino-3-Phenylbutyrique, Acide Bêta-phényl-gamma-aminobutyrique, Agente Gabaérgico, B-Phenyl-Gamma-Aminobutyric Acid, and Beta-Phenyl-GABA, Bêta-Phényl-GABA.

As per animal research, it helps to lower down the anxiety and other mental health disorder.

According to the Food Drug and Cosmetic Acts, the definition of dietary supplement that is used by human includes vitamin, herbs, amino acid, minerals, and other botanicals. But phenibut does not suitable for any of these categories.

This is the reason this substance considered as a misbranded agent as per FD & C act. Moreover, it is named as fenibut, phenigum, phonogram, and many more chemical names.

This chemical compound is not legal in the USA for chemical use.

What is Phenibut?

Phenibut Powder

Phenibut is used as anti-anxiety supplement prescribed in Russia. Moreover, According to BMJ journal case reports, it has been prescribed since 1960 to treat mental health, including depression, stuttering, vestibular, and other heart-related disorders.

This medication was firstly developed in union Soviet union and used for medical use in Russia, Ukraine, Latvia, and other soviet countries. on the other side, and it is prohibited in the US and Europe.

It works as a GABA –B agonist that helps to stimulate the GABA receptor. GABA receptor helps to calm the mind and reduce anxiety & nervousness.

Apart from this right side, it also has a wrong side, including euphoria, addiction, and withdrawal symptoms. The government has regulated the manufacturing process of this compound in Australia.

It refers to as a controlled drug, that means if any manufacturing unit or a person cannot start production without the permission of their government organization.

These are regulated by the organization of government that comes under the controlled substances act use.

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What Are the Good Effects of Phenibut Supplement?

It helps to treat mental health disorder such as anxiety, depression, fatigue, insomnia, irregular heartbeat, post-traumatic stress disorder, tension, and other condition. As per the study, it acts as a tranquillizer agent that enhances mental health.

Moreover, it has a characteristic of GABA receptor, which helps to calm the mood and make you feel happier. Although it is phenibut is a mental stimulating agent, it acts as a sleep aid, cognitive booster, and give strength to the body.

What Are the Side Effects of Phenibut?What Are the Side Effects of Phenibut

Overall, it is suitable for mental health, and addictiveness of this supplement is low, but, it is one of the harmful compounds for human health. Moreover, it is available on online shopping portals and used by many people worldwide.

Most of the people are using it illegally without knowing the actual dose that is decided by many controlled drug agencies. Moreover, this can be a dangerous drug if you do not a substantial quantity of use.

Once you use it with the combination of benzodiazepines, you can get dependent on it. Although, once you get dependent on this drug, there may be severe withdrawal symptoms can appear like irritability and anger.

It might be extremely tough to get rid of the dependency of this drug. The common side effect can be appeared by using this drug are the following: –

  • Hangover effects
  • Dizziness
  • Nausea
  • Insomnia
  • Tension
  • Stress
  • Depression
  • Fatigue
  • Fear

What are the Effects of Phenibut?

For the most patient, it has a mild effect on the brain. It has a remarkable ability to suppress symptoms of mental health and, in particular, social stress. For some patient, phenibut has sleepy effects, or it can create sedation.

It may also elevate the effects of euphoria when used recreationally. All of the products are the result of it being a GABA analogue. Structurally, it is similar to GABA receptor presents in the brain, which is a relaxing neurotransmitter responsible for

Moreover,it also crosses the blood-brain barrier because it is similar to GABA receptor.

It tends to create extreme euphoria when you take at a higher dose., and the effects of this supplement is also long-lasting for most patient. As per case the studies, sometimes, at lower doses, phenibut can create sedation and euphoria or fear effects.

For example, at low doses, it will create effects can create mild stimulation and insomnia.

Apart from this, phenibut effects can include some level of respiratory problem. While respiratory depression is exceptional with phenibut, it can be when this is mixed with other depressant drugs.

Long Term Effects

One of the significant risks associated with this supplement is the formation of a chronic effect of dependency. For some people, this is even a short period. Some people develop a habit of phenibut after using it only once.

Phenibut withdrawal symptoms can be uncomfortable and challenging to deal with this supplement. For a few patients, phenibut withdrawal symptoms may include anxiety and depression, headaches, nausea, and agitation.

Even without dependence, phenibut can include persistence of depression and fatigue for a long duration. With long-term, a higher dose of phenibut, people may also suffer from the complications of their liver and blood, including fatty liver disease and eosinophilia.

Mixing of Phenibut and Alcohol

It is often common to mix phenibut supplement with other drugs or substances—one reason for mixing it with alcohol maybe because people are not aware that phenibut contraindication with alcohol.

There is a mindset of people; only the controlled substance or illegal drug is unsafe with alcohol. Apart from these, all are safe to take at any conditions.

Most people think that they can use it with alcohol or even opioids because phenibut is also operated in the treatment of mental health, including depression and anxiety.

As a simulator, it can raise the effects of alcohol at the brain.

When a person mixes it with alcohol, minimal side effects can appear. Another side effect can include disinhibition and sociability, or higher depression and sleepiness.

A few people who mix these substances, they might feel nausea and vomiting.

Is Phenibut Causes Addiction?

Phenibut Causes

Back in 2013, phenibut was listed as a psychoactive substance in the European Monitoring Centre for Drugs.

Users have been built their tolerance with this supplement. Over time, it is responsible for bringing a few changes in the brain receptor; this is the reason behind the addiction of this drug.

Withdrawal symptoms may be severe and can persist up to 2-3 week. As per the study of this substance, a range of both physical and physiological effects, it could undoubtedly be considered as an addictive substance for the brain.

Mostly addictive symptoms are related to behavioural and psychological effects. Moreover, the reason for the addiction is the changes in the brain receptor, such as stimulation of both dopamine receptors and GABA receptors. Changes in dopamine receptors lead to addiction.


Is Phenibut illegal?

It is legal and prescribed for clinical uses in a few countries of Sobiyat countries. despite this, it can available on shopping portals to purchase in the US. It may cause addiction in some patients that are why it is banned by the government in most countries.
Moreover, the withdrawal of addiction is easier than other addictive drugs. The severe addiction symptoms are like sedation, social irritability, depression, dizziness, fatigue, anxiety, insomnia and other symptoms are noticed.

What is Phenibut HCL?

It is a recreational drug and medicine that is used to treat mental health disorder including anxiety, depression, fear, irregular heartbeat, insomnia and many more. Moreover, it improves memory and learning skills.

Does Phenibut affect serotonin?

It is an anxiolytic drug that might increase the level of dopamine, which mood-enhancing neuro-chemical. It does not affect any neurotransmitter like GABA and serotonin but due to the uses of this supplement, it is noticed that reduction of non-epinephrine.

Does Phenibut feel like Gabapentin?

Phenibut has a similar structure as GABA receptor. It acts as a GABA agonist and helps to enhance the mood. On the other side, Gabapentin is an anticonvulsant used to treat seizures. Here, the mechanism is different for both drugs.

What are doses of Phenibut should you take for anxiety?

A recommended dose for this drug is 250mg to 1000mg for a single day. As per the study, the highest dose of this supplement is up to 3000mg is safe.

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