C-Peptide Test – Purpose, Results & Side Effects

C-Peptide Test

A C-peptide test measures the difference between produced insulin and injected insulin.  The presence of C-peptide indicates that your pancreas is producing insulin. Although it consists of 31 amino acids, it helps synthesis insulin in the pancreas.

Insulin is the natural hormone produced in our body that controls glucose levels. Both C-peptide and insulin release in equal amounts at the same time. So a C peptide test indicates how much insulin your body is producing.

This test shows the exact value of insulin, and measuring the C-peptide is good because it lives in the body for longer than insulin.

What is C-Peptide?

C-peptide was introduced in 1967 during the study of the biosynthesis of the insulin pathway. It provides the medium between the A- B chain of the insulin and creates the pathway in insulin production.

Initially, the only curiosity in c-peptide as an indicator of insulin production has excellent utility in getting the pathophysiology of TYPE 1 and TYPE 2 diabetes.

what is c-peptide

During the initial study of C-peptide, it has found that the bioactive peptide helps in the microvascular blood flow and tissue health.

C peptides play a significant role in synthesising insulin from the pancreas. Some research articles have stated the benefits of C peptide TYPE 1 Diabetes in recent years. Moreover, it helps to improve kidney function, nerve cells function, liver function, and blood flow.

As per Diabetologia 2008,51 175, when isolated red blood cells were combined with C peptide, C peptide cleared the way of glucose from the blood. It released the ATP(adenosine triphosphate) energy stimulator of cells.

How Is the C-Peptide Test Performed?

The C-Peptide test is the way to analyse insulin production in the body. To perform this test, a patient has to give their blood sample in the laboratory.

A lab assistant will take the blood sample from your vein with a needle and send it to the laboratory for further analysis.

A urine test for the C-Peptide test is also performed. This test is known as a 24hrs urine sample. Your lab assistant may ask you to collect urine in the sterile bottle.

The lab assistant may ask you to collect urine for 24 hours for the urine sample test. He will give a few instructions for the C-peptide test of urine. Here, we guide you with the procedure of collecting 24hrs urine samples.

  • Flush the first urine in the morning and clear your bladder.
  • After that, for the next 24hrs, you have to save your urine in the provided sterile zar
  • Store the urine in a cold area like a refrigerator or use an icebox to keep it cool
  • . Submit the sample with the icebox at the laboratory for further analysis of the c-peptide test.

Why Do You Need to Get Tested a C-Peptide Blood Test?

In the condition of both hyperglycemia and hypoglycemia, you should go for a C-Peptide blood test. Insulin is one hormone that promotes glucogenesis, lipogenesis, and protein synthesis.

If you have TYPE 1 diabetes, the body makes low insulin or stops insulin synthesis. The body patient with type 1 diabetes does not support the insulin-peptide pathway.

c peptide test, c-peptide blood test
Source:- American Association for clinical chemistry

If you have TYPE 2 diabetes, the pancreas produces sufficient insulin, but the patient of the body does not utilise it properly. It may cause a high level of C -peptide in the bloodstream.

The C- Peptide test plays a significant role in detecting hyperglycemia and hypoglycemia. The C- peptide test also helps analyse diabetic therapy and pancreas tumors.

If you are suffering from the following symptoms, you should visit a healthcare practitioner. They might recommend you C-Peptide blood test.

  • Rapid Irregular Heartbeat
  • Blurred vision
  • Sweating
  • Confusion
  • Abnormal hunger

What are Normal Results of C Peptide?

A standard value of the C peptide test is 0.5 to 2.0 nanograms per milliliter (ng/mL). The usual range of reference may slightly vary from one lab to another.

What are the Abnormal Results Mean?

C-Peptide levels depend on insulin production or the sugar levels present in the blood. The presence of a normal referral range of c peptides means your body is producing sufficient insulin. A low level of c-peptide means your body is not producing insulin in a sufficient amount.

  • If you went for the test on an empty stomach, your results might show a low peptide level and a low sugar level.
  • If your report shows a low level of c-peptide and a high level of blood sugar, the report may refer to abnormal.

What If Your C Peptide Level is High?

A high c peptide level indicates that your pancreas produces insulin more than average. It indicates two directions; first, you have type 2 diabetes or a chance of pancreatic cancer.

What Medical Conditions Can Cause High C-Peptide Levels?

If your C-peptide level is higher, it indicates that your body is synthesizing more peptides than average.

There are some causes of high C Peptide levels in the body.

  • Chances of developing insulinoma, a small tumour in the pancreas, synthesize an excess amount of insulin.
  • Insulin resistance happens when pancreatic cells produce insulin, but your cells have low sensitivity towards insulin. Insulin resistance may lead to high insulin and high blood sugar levels.
  • Kidney infection

How much Does a C Peptide Test Cost?

The average C-peptide blood test price varies from city to city. It basically depends on the locality, town, and quality of apparatus labs are using. Generally the indicative C-peptide test prices can be found to be around 600-2000 rupees.

Similar Posts